Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma

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Hemophagocytic lymphohistiocytosis complicating a T-cell rich B-cell lymphoma

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T cell histiocyte rich large B cell lymphoma (THRLBCL) is a rare subtype of non-Hodgkin's lymphoma characterized by malignant B cells with reactive T lymphocytes. The pathophysiology is thought to involve cytokine-mediated evasion of T cell immune response by malignant B cells. It usually presents at an advanced stage with extranodal involvement. An extremely unusual manifestation of the diseas...

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ژورنال

عنوان ژورنال: BMC Hematology

سال: 2016

ISSN: 2052-1839

DOI: 10.1186/s12878-016-0065-5